https://multicellml.org/wiki/ 2026-04-08T01:03:50+00:00 https://multicellml.org/wiki/ https://multicellml.org/wiki/lib/exe/fetch.php?media=logo.png text/html 2019-08-21T15:40:18+00:00 Anonymous (anonymous@undisclosed.example.com) https://multicellml.org/wiki/doku.php?id=hackathon&rev=1566402018&do=diff Hackathon 2019 [ Hackathon 2019] Aim Multicellular spatial models have become an essential tool in quantitative biology and multiple model formalisms (incl. rule-, energy- or force-based cell and tissue mechanics) and simulation frameworks coexist. Progress towards software interoperability and reproducibility requires a novel model description language and conversion library, complementing SBML. Building on the community‘s practical experiences with multiple formalisms and simulators, we… text/html 2022-09-23T12:46:30+00:00 Anonymous (anonymous@undisclosed.example.com) https://multicellml.org/wiki/doku.php?id=prototype&rev=1663937190&do=diff Prototype implementation of MultiCellML concepts in MorpheusML We are using MorpheusML to test the concepts of MultiCellML, e.g. spatial scoping that allows to model coupling between properties of multiple individual cells that can be dynamically generated (e.g. through cell division) and destroyed (e.g. through apoptosis) but use their own copies of the same entities (biochemical molecules) with the same symbol name (irrespective of the computational index of each individual cell). The individ… text/html 2025-03-20T17:05:15+00:00 Anonymous (anonymous@undisclosed.example.com) https://multicellml.org/wiki/doku.php?id=repository&rev=1742490315&do=diff Model Repositories Several model repositories host the xml-based model descriptions for computer-readable and readily executable multicellular models, including * Spatio-temporal model of YAP activation during liver regeneration * Spatio-temporal model of Wnt-Hh interaction in the liver * and further models at LiSyM SEEK * Morpheus model of spatio-temporal liver zonation from Wnt-Hh crosstalk * Morpheus model of spatio-temporal YAP/Hippo pathway activation during liver regeneration … text/html 2021-04-19T14:18:59+00:00 Anonymous (anonymous@undisclosed.example.com) https://multicellml.org/wiki/doku.php?id=sbml&rev=1618841939&do=diff Concept of SBML extensions towards MultiCellML Building on existing SBML Level 3 core (A) and (draft) extensions, MultiCellML is designed as a composed model format (E) that uses parts of the dynamic populations package (C) and parts of the static spatial compartments package (B). The latter will be generalized to dynamics of spatial structures (D). text/html 2026-04-07T05:43:59+00:00 Anonymous (anonymous@undisclosed.example.com) https://multicellml.org/wiki/doku.php?id=sidebar&rev=1775540639&do=diff Concepts * SBML extension * Prototype implementation Models * More repositories * COMBINE FAIRSPACE * MorpheusML models in BioModels * Morpheus model repository Events * COMBINE 2018 * COMBINE 2019 * MultiCellML Hackathon 2019 * COMBINE 2020 * HARMONY 2021 * COMBINE 2021 * HARMONY 2022 * Virtual-Tissue Summer School and Hackathon 2022 * COMBINE 2022 * HARMONY 2023 * Multicell Virtual Tissue Modeling Summer School & Hackathon 2023 * COMBINE 2023 * Lorent… text/html 2026-01-16T19:41:00+00:00 Anonymous (anonymous@undisclosed.example.com) https://multicellml.org/wiki/doku.php?id=start&rev=1768592460&do=diff Welcome to the COMBINE working group for standardization of multicellular model descriptions. News: OpenVT Reproducible Agent-Based Multicellular Model Competition The Open Virtual Tissues (OpenVT.org) initiative has announced the winners of the 2025 Reproducible Agent-Based Multicellular Model Competition. One model based on CompuCell3D and two models based on the Morpheus modeling framework made it to the podium and were celebrated at the